Ivarsson, being employed by and owning share options in Moderna Dr. Han, being employed by and owning stock and stock options in Moderna Dr. Leav, Deng, and Zhou being employees of Moderna Dr. Knightly, being employed by and owning stock and stock options in Moderna Drs. Pajon, being employed by and owning stock in Moderna Dr. Bennett, being employed by and owning stock and stock options in Moderna Dr. Graham, holding pending patent WO/2018/081318 on prefusion coronavirus spike proteins and their use and pending patent 62/972,886 on 2019-nCoV vaccine Dr. Neuzil, receiving grant support from Pfizer Dr. Creech, receiving grant support from Merck, consulting fees from Horizon Pharma and GSK, and fees for serving on a data and safety monitoring board from Astellas Dr. Rouphael, receiving grant support from Pfizer, Merck, Sanofi–Pasteur, Eli Lilly, and Quidel Dr. Baden reports being funded by the NIH to conduct clinical trials in collaboration with Crucell/Janssen and Moderna Dr. (Funded by the Biomedical Advanced Research and Development Authority and the National Institute of Allergy and Infectious Diseases COVE number, NCT04470427.).Ĭopyright © 2020 Massachusetts Medical Society.ĭr. Aside from transient local and systemic reactions, no safety concerns were identified. The mRNA-1273 vaccine showed 94.1% efficacy at preventing Covid-19 illness, including severe disease. Serious adverse events were rare, and the incidence was similar in the two groups. Moderate, transient reactogenicity after vaccination occurred more frequently in the mRNA-1273 group. Severe Covid-19 occurred in 30 participants, with one fatality all 30 were in the placebo group. Efficacy was similar across key secondary analyses, including assessment 14 days after the first dose, analyses that included participants who had evidence of SARS-CoV-2 infection at baseline, and analyses in participants 65 years of age or older. person-years 95% confidence interval, 48.7 to 65.3) and in 11 participants in the mRNA-1273 group (3. Symptomatic Covid-19 illness was confirmed in 185 participants in the placebo group (56. More than 96% of participants received both injections, and 2.2% had evidence (serologic, virologic, or both) of SARS-CoV-2 infection at baseline. The trial enrolled 30,420 volunteers who were randomly assigned in a 1:1 ratio to receive either vaccine or placebo (15,210 participants in each group). The primary end point was prevention of Covid-19 illness with onset at least 14 days after the second injection in participants who had not previously been infected with SARS-CoV-2. Persons at high risk for SARS-CoV-2 infection or its complications were randomly assigned in a 1:1 ratio to receive two intramuscular injections of mRNA-1273 (100 μg) or placebo 28 days apart. This phase 3 randomized, observer-blinded, placebo-controlled trial was conducted at 99 centers across the United States. The mRNA-1273 vaccine is a lipid nanoparticle-encapsulated mRNA-based vaccine that encodes the prefusion stabilized full-length spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes Covid-19. Vaccines are needed to prevent coronavirus disease 2019 (Covid-19) and to protect persons who are at high risk for complications.
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Be loved, be hated, be admired, or be feared! Opinion based conversation system: Gain favors by interacting with other characters frequently. Hunt for rare and unique species of all genders and races: Using your trusty tranquilizer long rifle, or go feral and capture with your bare paws!įully customize your character: Select from general body shape, including species, breasts, genitalia, and tail, down to the color and pattern of your skin and pupil style. Will your crew grow to love you as an equal ship commander, or will they idolize you as a renowned hunter? Travel between islands on a ship with your trusted ship crew, hunt rare species with a tranquilizer rifle or capture with bare paws,and sell to the highest bidder after rigorous sampling of the prey. Continued abuse of our services will cause your IP address to be blocked indefinitely.Hunt and Snare is a Furry Third Person Shooter with a strong focus on sexual themes and character interaction. Please fill out the CAPTCHA below and then click the button to indicate that you agree to these terms. If you wish to be unblocked, you must agree that you will take immediate steps to rectify this issue. If you do not understand what is causing this behavior, please contact us here. If you promise to stop (by clicking the Agree button below), we'll unblock your connection for now, but we will immediately re-block it if we detect additional bad behavior.
It’s been a long time since I’ve truly fallen in love with a cleansing oil. Now on to the products! SEKKISEI Treatment Cleansing Oil And consistent use yields significant results. Vitamin C is also known to increase collagen production and inhibit melanin synthesis, improving firmness and elasticity and reducing dark spots and hyperpigmentation. It’s an excellent antioxidant, making it preventative against skin-aging free radical damage. Ascorbyl glucoside converts to ascorbic acid in skin, and there’s no lack of research into the benefits of ascorbic acid. Likewise, angelica acutiloba extract appears in some Sulwhasoo products I’ve loved, most notably the Concentrated Ginseng Renewing Cream.įor the brightening claims, however, I’m pleased to also see ascorbyl glucoside, a milder and more stable form of vitamin C, in the SEKKISEI Emulsion. Sulwhasoo uses it in some products as well. I’ve used several Taiwanese products that contained this ingredient and resulted in a brighter and more translucent look, though it’s impossible to say whether that’s due to the coix seed or something else in their cocktail of extracts. My personal, anecdotal experience with coix seed extract has been very positive. I also came across an additional hint that angelica may defend against collagen degradation in UV-exposed skin. Some research suggests that melothria may deliver antioxidant and anti-aging benefits. There’s a hint of evidence that coix seed extract may help inhibit the formation of melanin. I’m not really finding much solid English-language research into the potential skincare benefits of these ingredients. SEKKISEI emphasizes moisturization and brightening in their marketing, claiming that continuous use of their products will minimize existing dark spots, help prevent new hyperpigmentation, and increase the translucency of skin for an overall more luminous appearance thanks to the their “translucency recipe,” which includes coix seed, angelica, and melothria extracts. With that being said, I can’t remember trying any particularly herby Japanese products, so this is a first. Scientific research into the topical use of herbs and extracts tends to be much thinner than it is for first-line actives like retinoids and vitamin C, but I’ve never let that stop me from giving the intriguing-sounding ones a chance on my own face. Intro to SEKKISEI: Claims and IngredientsĪs you might have noticed from my love of brands like South Korea’s Sulwhasoo and Taiwan’s Naruko, both of which often use extracts and formulas inspired by traditional Korean and Chinese herbal medicine, I love the herbal concept in cosmetics. I also remembered just how beautiful their packaging is. So I said yes, a package appeared on my doorstep bearing the items in question, and here we are. I have my old favorites but hadn’t found anything else I’d really loved in a while. I’d just finished my book and found myself with more time and energy on my hands than I’d had in a while. Until now.Ĭostco currently carries the brand, and SEKKISEI’s US representatives reached out to ask if I’d work with them to get the word out about two of their products in particular, the Treatment Cleansing Oil and Emulsion. I was too overwhelmed by other products and projects to give them a chance. I loved the gorgeous blue bottles and jars and found their emphasis on herbal ingredients compelling, but, at the time, not quite enough. I first encountered the SEKKISEI products a few years ago. This is what happened with me and Kose’s SEKKISEI skincare brand. Sometimes you encounter a product at the wrong time and pass it by, only for that product to come back into your life at a later date, when you’re ready to appreciate it. □Spinning & Static Modes: You can switch the spinning mode and stationary mode through a twist on the bottom screw with the tool included.Once properly assembled, this dance pole can hold up to 230kg/500lb. □Substantial quality with fine workmanship: The portable dancing pole is constructed of seamless steel tubes in a glossy chrome finish, featuring a smooth surface to ensure the safety of your every move.□Specifications: Color: silver Material: chrome-plated steel Pole diameter: 45mmWeight capacity: 500lb Overall dimensions: 15.5" L x 15.5" W x 85"-108.5"H/ 1.3' L x 1.3' W x 7'-9' H.You can use it for physical exercise, stage performances, or even teach classes at home, the club, bar, gym, yoga room or dance studio. 【Suitable For All Pole Dance Enthusiasts】This height-adjustable static/spinning dancing pole is perfect for pole fitness lovers of all levels.Plus, the silicone rubber adds some extra friction, making the whole setup even more stable. 【Domes With Silicone Rubber】The rim of the top and base domes is carefully wrapped with silicone rubber to keep both the ceiling and floor free of any permanent markings.【Easy-to-assemble & Removable】The dance pole is super easy to assemble and even easier to remove! You can break it down into pieces for simple moving and storage without any complicated bolts, screws, or drilling.The static mode is great for building up strength and perfecting tricks, and once you're ready, the spinning mode adds a graceful flow to your movements. 【2 Modes For Great Versatility】The steel dance pole has both spinning and static modes for beginners and professionals.And, thanks to its 2.5 cm / 1″ long solid threaded connections, you can be sure it's stable when in use. 【Safe & Sturdy】This professional dance pole is crafted from heavy-duty steel with chrome finish for a regular grip and high strength and durability.Easy to Storage: The atom parts and links are color coded to national standards for ease of identification, and the pieces come in a slim plastic box for convenient storage.Perfect Gift for Learning: Our chemistry kit is modeling simple and small to more advanced and complex chemical structures for schools and college level, students of all ages, researchers and enthusiasts.
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You've probably never heard the original version of "Let It Snow."Īfter charting for the first time in 2018, Dean Martin's "Let It Snow" reached another important milestone in 2019: An official music video for the song was uploaded to YouTube in November. The full title of "Let It Snow" is a mouthful.Ĭahn and Styne's tune was first recorded in 1945 and released under the full title "Let It Snow! Let It Snow! Let It Snow!" Today, the wordy title is commonly shortened to the simpler "Let It Snow." 4. Instead of heading to the beach, they decided to stay inside and write a song that would transport them to the winters of their youths. Lyricist Sammy Cahn and composer Jule Styne had to use their imaginations when writing "Let It Snow." The two were struggling to endure one of the hottest days on record in Southern California in July 1945. "Let It Snow" was written during a heatwave. So feel free to continue singing "Let It Snow" into the New Year and beyond. Fire, popcorn, and winter weather are all mentioned, none of which are uniquely Christmas-y. The song concludes with the singer once again expressing their desire for snowfall to continue."Let It Snow" has become a regular part of radio stations' holiday playlists, along with tracks like "Rudolph the Red-Nosed Reindeer" and " All I Want for Christmas Is You." But unlike those songs, "Let It Snow" contains no references to Christmas. The singer repeats their belief that the embrace of their loved one will keep them warm on their journey home. The singer repeats their desire for the snowfall to continue. The singer is comforted by their loved one's affection. The singer and their loved one are still saying their goodbyes. The warmth of the fire inside is beginning to fade. The singer believes that being embraced tightly by their loved one will keep them warm on their journey home. The singer would feel better about leaving if their loved one embraces them tightly. The singer dislikes the thought of leaving the warm setting to go out in the snow. The singer anticipates a romantic ending to the evening. The room is dimly lit to match the cozy atmosphere. The singer is prepared to enjoy some snacks while staying in. The snowfall is expected to continue for some time. The singer expresses their desire for snowfall to continue. The singer and their loved one have no reason to leave the cozy setting. The singer welcomes the warmth of the fire inside. The singer describes the weather outside as dreadful. It's a comforting reminder that no matter how cold and dark things may seem, the love we share can keep us warm and hopeful. Overall, "Let It Snow" is a classic holiday song that highlights the beauty of winter while also emphasizing the warmth of love and companionship. Even as the fire dies down and it's time to say goodbye, the singer takes comfort in knowing that as long as they have each other's love, they'll be able to weather any storm. The repetition of "Let It Snow" seems less about accepting the weather and more about accepting the love they share. While the storm outside may be daunting and uncomfortable, the singer finds solace in their partner's embrace. The turning point in the song is the final verse where the focus shifts from the storm to the singer and their love interest. The chorus refrains with the invitation to Let It Snow, repeating the phrase three times to solidify the acceptance of the winter wonderland. The second verse emphasizes the relentless nature of the storm, with the singer seeming resigned to stay inside and pass the time by popping corn. The first verse sets the scene with the contrast between the frightful weather outside and the delightful warmth of the fire. In Michael Bublé's version of Let It Snow, the imagery of a cold winter night is juxtaposed with the warmth and coziness of a fire. Tesla, at its recent battery day, outlined growth expectations that implied the company would need 80% of the world’s current nickel production in 10 years. “Copper is the oil of the clean energy economy.” “If you want to overhaul the electric grid, you need copper,” says White. Sandfire Resources, an Australian gold and copper miner also looks attractive. White currently likes Grupo Mexico, a misunderstood conglomerate with a controlling stake in Southern Copper, which mines in Mexico and Peru. “Lithium is abundant, while copper is a precious metal.” If you want to fight climate change, copper is the oil of the clean energy economy.” Solar and wind generators use roughly 10 times the copper of fossil fuel plants for comparable generation capacity, while electric vehicles need at least three times more copper than an internal combustion engine. He sees better returns ahead for the companies that supply the raw materials that go into batteries rather than those that sell the finished product.ĭon’t get hung up on lithium, a main ingredient in lithium ion batteries, he says. To invest in it, it’s best to apply a global perspective, says Lucas White, portfolio manager at GMO, who manages $1.1 billion in natural resources strategies and has generated 23% annualized returns the past five years. Indeed, the battery trend is bigger even than Texas. Copper and nickel miners like Norilsk and Sandfire will benefit from a battery boom. Most annual crops can be used apart from cotton and sweet potatoes, which are host plants for Helopeltis bugs, major pests of cashew. Intercropping can be done before the canopies close. Do not plant seeds that are more than one year old.Sundry seeds for planting for several weeks to prevent mold and rotting.Those that float have poor germination and growth potential. Place the seeds in a bucket of seawater (100 g salt per 5 liters of water) and select the seeds that sink for planting.Proper seed selection from healthy, high-yielding trees is important, and it can be done by sorting out seeds by the water density method: High-density planting of cashew at a closer spacing of 4 m X 4 m (625 plants/ ha) in the beginning and thinning out in stages to maintain a final spacing of 8 m X 8 m in the tenth year is also recommended. The holes should be 60 cm by 60cm so that they can be able to collect water during the rainy season which will be used during the dry season.Ĭashew trees are generally planted with a spacing of 7.5 m X 7.5 m (175 plants/ ha) or 8 m X 8 m (156 plants/ ha) is recommended. In propagation by direct seeding 3 seeds are planted in the planting hole and two months after germination the weak seedlings are uprooted leaving the strong ones to grow. In the Coastal lowlands, the best time for planting is between April to June.Ĭashew nuts are usually propagated through seed or grafted seedlings. The Portuguese introduced cashew to Mozambique in the 16th century where it flourished, forming extensive forests eventually, it also became dispersed in East Africa along the coastal plains of Kenya and Tanzania.Ĭashew nuts should be planted at the beginning of the rainy season. The cashew apple is pear-shaped and red to yellow.Ĭashew trees can reach a height of 12 m (39.4 ft) and have an economic lifespan of 25 years after which time they are replaced in commercial plantations.Ĭashew originates from Brazil. The tree produces numerous pinkish-white flowers on drooping panicles and a kidney-shaped true fruit (nut) which is approximately 3 cm (1.2 in) long with a grey-brown shell and develops from a fleshy accessory fruit, sometimes referred to as the 'cashew apple'. The leaves are smooth with pronounced veins and midrib and possess petioles that are swollen at their base. The thin foliage of the tree is limited to the ends of the branches and is made up of oval-oblong leathery, shiny dark green leaves. The cashew tree has a branching main trunk and characteristic domed crown. Cashew is an evergreen tree with deep tap roots, grown for its edible fruits (nuts). To Store: That said, leftovers can be stored in an airtight container in the refrigerator for up to 1 day. I recommend only slicing and assembling as much apple as you plan to eat! This snack is best enjoyed fresh as the apples will brown and the toppings may lose their crunch after a short period of time. Serve! If you are making them for a crowd, you can repeat the process with additional apples for multiple layers. The nut butter will help the toppings to stick.ĥ. Sprinkle your desired toppings evenly over the apples and nut butter. If the nut butter that you are using is thick, heat it in the microwave for 15-30 seconds in order to make it easier to drizzle on.Ĥ. If using a drippy nut butter (such as homemade macadamia butter) it may be runny enough to simply spoon it over the apple slices. Spread the apples out on a plate in a single layer, overlapping just enough to fully cover the plate.ģ. If you are planning on eating them right away as a snack, it probably isn't necessary but if you are anticipating not eating them all right away, it can help them to last.Ģ. TIP: To prevent browning, you can toss the sliced apples with a tablespoon of lemon (or lime) juice. You could also cut the apple in quarters and then cut the quarters each into even slices. I slice from two opposing sides first and then slice the thin remaining portion so that I have large circles and a few small rectangular pieces. Honey Cinnamon Granola- I love the pairing of the cinnamon with the apples!ġ.Toppings- These are my favorite toppings but almost anything goes! See the "Make It Your Own" section below for more ideas.However, you could use whatever nut butter you like or use sunflower seed butter for a nut free option. Nut Butter- I love using homemade macadamia nut butter on my apple nachos- it is very drippy and easy to spread and I love how buttery and creamy it is.If you are making these to share, you could use two apples of two different types for some extra flavor variation. Gala and granny smith apples are my favorite go-tos. Apple- You can use any apple you like the taste of.Whether you make them to entice kids to eat fruit, or simply to make it easier for your inner kid to eat an "apple a day", they are sure to be a hit!Īnd if you're looking for more ways to make fruit fun, check out these Rice Paper Candy Straws. Way different than classic nachos (like this White Cheddar Chicken version) but equally as fun, they are quick to make and delicious to eat. Turn them into nachos, though, and it's something to be excited about! The sky is the limit when it comes to this fun recipe so get creative and make it your own! Jump to:Īpple nachos are one of my favorite healthy snacks! Because sometimes, simply eating an apple and some nuts. Crispy apples are thinly sliced and topped with creamy nut butter and crunchy toppings. Nothing like the classic cheesy topped tortillas version, these Healthy Apple Nachos make for a fun breakfast, snack or even dessert. |
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